![]() Scientists don't yet understand what causes SPS, but research indicates that it is the result of an autoimmune response gone awry in the brain and spinal cord.It is frequently associated with other autoimmune diseases such as type-I diabetes, thyroiditis, vitiligo, and pernicious anemia.SPS affects twice as many females as males.Who is more likely to get stiff-person syndrome ? People with SPS may be afraid to leave the house because street noises, such as the sound of a car horn, can trigger spasms and falls. Many fall frequently because they do not have the normal reflexes to catch themselves. ![]() Some people may be too disabled to walk or move. ![]() Over time people with SPS may develop hunched over postures. ![]()
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